1908: first state bans booze1966: last state bans booze ban

Mississippi was the first state to prohibit drinking alcoholic beverages, in 1908.

Mississippi was the first state to ratify the 18th Amendment to the United States Constitution, beginning the era of Prohibition, 1919-1920.

Mississippi was the last state to end statewide prohibition in 1966, 33 years after national prohibition had ended.